This could be the start of something really important. Mosquito-borne diseases seem to be becoming more common and this seems like the first step in reducing their impact.
Whilst malaria tablets are very effective, it is very easy to forget or lose a tablet, exposing yourself to risk. A vaccine is much more foolproof!
A malaria vaccine using a weakened form of the parasite has passed a "critical milestone" in human safety trials, say researchers. Doctors used a genetically modified form of malaria that was unable to cause a full infection in people. Trials suggested it was safe and generated a good immune response. The malaria parasite goes through multiple stages both in mosquitoes and inside the human body. The team at the Centre for Infectious Disease Research deleted three genes from the parasite so it could not infect liver cells. The idea is "infecting" people with the weakened parasite will expose the immune system to malaria, but the parasite will not be able to complete its lifecycle to cause disease. Ten people took part in the trials. No-one went on to develop the disease and there were no severe side-effects to the treatment.